Expression of γ-adducin is associated with regions of morphogenetic cell movement in the chick embryo

نویسندگان

  • Jun Akai
  • Kate Storey
چکیده

The adducin family of cytoskeletal proteins are known to mediate actin driven cell movements. Here we describe the cloning and expression pattern of a gene encoding gamma-adducin in the chick embryo. Expression of this gene is strikingly restricted to the epithelial cell layer (with a few exceptions including emerging notochord and lateral mesoderm). Gamma-adducin is detected at particularly high levels in cell populations undergoing important morphogenetic movements, such as epiblast approaching the primitive streak, regressing spinal cord primordia and closing neural tube.

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عنوان ژورنال:
  • Mechanisms of Development

دوره 119  شماره 

صفحات  -

تاریخ انتشار 2002