Expression of γ-adducin is associated with regions of morphogenetic cell movement in the chick embryo
نویسندگان
چکیده
The adducin family of cytoskeletal proteins are known to mediate actin driven cell movements. Here we describe the cloning and expression pattern of a gene encoding gamma-adducin in the chick embryo. Expression of this gene is strikingly restricted to the epithelial cell layer (with a few exceptions including emerging notochord and lateral mesoderm). Gamma-adducin is detected at particularly high levels in cell populations undergoing important morphogenetic movements, such as epiblast approaching the primitive streak, regressing spinal cord primordia and closing neural tube.
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عنوان ژورنال:
- Mechanisms of Development
دوره 119 شماره
صفحات -
تاریخ انتشار 2002